Publications

2023

E. Boero, R. D. Gorham Jr., E. A. Francis, J. Brand, L. Teng, D. J. Doorduijn, M. Ruyken, C. Lehmann, A. Verschoor, K.P.M. van Kessel, V. Heinrich, and S.H.M. Rooijakkers, “Purified complement C3b triggers phagocytosis and activation of human neutrophils via Complement receptor 1”, Accepted for publication in Scientific Reports.

2022

E. A. Francis and V. Heinrich, “Integrative experimental/computational approach establishes cellular protrusion as the primary driving force of phagocytic spreading by immune cells”, PLOS Computational Biology, Aug 2022, https://doi.org/10.1371/journal.pcbi.1009937

E. A. Francis, H. Xiao, L. Teng, and V. Heinrich, “Mechanisms of frustrated phagocytic spreading of human neutrophils on antibody-coated surfaces”, Biophysical Journal, Dec 2022, https://doi.org/10.1016/j.bpj.2022.10.016

2018

E. A. Francis and V. Heinrich, “Mechanistic understanding of single-cell behavior is essential for transformative advances in biomedicine”, The Yale Journal of Biology and Medicine, Sept. 2018, 91(3):279-289.

E. A. Francis and V. Heinrich, “Extension of chemotactic pseudopods by nonadherent human neutrophils does not require or cause calcium bursts”, Science Signaling, Mar 2018, 11(521):eaal4289.

2017

V. Heinrich, W.D. Simpson, and E. A. Francis, “Analytical prediction of the spatiotemporal distribution of chemoattractants around their source: theory and application to complement-mediated chemotaxis”, Frontiers of Immunology, May 2017, 8:578.

E. A. Francis and V. Heinrich, “Quantifying the sensitivity of human immune cells to chemoattractant”, Biophysical Journal, Mar 2017, Vol. 112, Iss. 5, p834-837.